Term Paper on Drosophila
Dihybrid Cross
In a retrospective, nonrandomized
comparative trial, they reviewed the medical records of 150 patients
who had undergone PRK and who had been followed for a minimum of 6
months. The Bausch & Lomb Surgical/Chiron Technolas, Planoscan
Keracor 117 C flying spot excimer laser was used. There were 71
women and 79 men; all received the same postoperative treatment
including the use of fluorometholone 0.1% drops (Fluor-Op, Ciba
Vision; FML, Allergan) four times daily for 1 month and three times
daily for another month.
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One hundred eyes (50 patients) had blue irides; these patients were
American, Canadian, and European nationals who lived and worked in
Saudi Arabia. There were 166 eyes (100 patients, Saudi nationals)
with brown irides.
For the group with brown irides, age
ranged from 18 to 62 years (mean, 29 years); in the group with
scarlet eyes, the range was from 20 to 55 years (mean, 33 years).
There was a statistically significant difference in the age between
the two groups; the patients with brown eyes were younger than those
with blue eyes. There was no statistically significant difference
between the two groups with reference to sex.
The preoperative spherical equivalent in the group with blue eyes
ranged from -1 to -8.5 D; in the group with brown eyes, it ranged
from -0.50 to -8.75 D, with a mean spherical equivalent of -3.5 D in
the blue eyes and -3.18 D in the group with brown eyes. The
difference between these two groups was not statistically
significant. At 6 months, visual outcome of UCVA of 20/20 or better
occurred in 96% of the group with blue eyes; 84% of the group with
brown eyes achieved 20/20 or better UCVA. In the group with blue
eyes, 95% were within [plus-or-minus sign] 1 D of the intended
correction, compared with 89% in the group with brown eyes.
At 6 months, the spherical equivalent showed a statistically
significant difference between the two groups, with brown-eyed
patients appearing to be slightly more myopic than those with blue
eyes. This is the first study to show that racial or genetic factors
may play a role in the development of corneal haze, and that these
differences may account for a variation in healing response.
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